APR host Zamalek SC on 16 October as the 2nd Preliminary Round opens

Zamalek SC begin their 2nd Preliminary Round tie away to APR at 16:00 GMT on 16 October. The return leg is scheduled for 24 October at 17:00 GMT. Zamalek SC arrive having beaten Port 6-1 on aggregate, winning 2-1 away and 4-0 at home.

Pyramids FC and Renaissance Berkane on the opening day

The 16 October programme starts at 13:00 GMT with EL Merriekh Bentiu v Pyramids FC. Pyramids FC went through against GOR Mahia 7-1 on aggregate, while EL Merriekh Bentiu beat Heegan 4-0 over the two legs. At 16:00 GMT, alongside APR v Zamalek SC, Star Sport Academy host Renaissance Berkane. Star Sport Academy were level 1-1 on aggregate with Medina United in the previous round.

On 17 October, CFFA host Young Africans at 12:00 GMT. The return leg comes soonest of all, on 21 October at 16:00 GMT. Young Africans qualified 3-2 on aggregate against Gaborone United, and CFFA beat Lijabatho 3-1.

TP Mazembe, Orlando Pirates and Simba on 17 October

TP Mazembe host Club Africain at 13:00 GMT. Club Africain progressed past Djoliba 3-2 on aggregate. At the same hour, African Stars welcome Orlando Pirates. African Stars were level at 3-3 with Mangasport after the 1st Preliminary Round, while Orlando Pirates beat La Cure Waves 3-1 on aggregate. The return leg is on 23 October at 17:30 GMT.

At 16:00 GMT, 15 de Agosto host Simba. Simba won 7-1 on aggregate against Be Forward Wanderers, and 15 de Agosto beat Fomboni Club 5-0. The return is on 25 October at 13:00 GMT.

Seven ties begin on 18 October

The busiest day is 18 October. At 13:00 GMT, Enugu Rangers host MC Alger, who beat NIGELEC 5-0 on aggregate. Scotland Mabvuku welcome Petro de Luanda, 3-2 winners over Songo, and Sidama Bunna host Al Hilal Omdurman. Both of those sides won 3-0 on aggregate last time out, Sidama Bunna against Aiglons and Al Hilal Omdurman against Aigle Noir.

At 15:00 GMT, Wiliete host Mamelodi Sundowns. At 16:00 GMT, Horoya entertain Al Merreikh. Horoya got past JS Saoura 3-2 on aggregate. At 17:00 GMT, Asswehly, who beat KVZ 4-0 on aggregate, host ES Tunis. Teungueth, 2-0 winners over Canchungo, host Colombe at the same time. Maghreb Fès host ASEC Mimosas at 18:00 GMT. ASEC Mimosas beat ASC Kara 3-2 on aggregate.

Level aggregates behind several sides

Several teams in this round come off ties that finished level on aggregate: Nouadhibou (1-1 with Vipers), Colombe (0-0 with Stade Malien Bamako), San-Pédro (3-3 with Rivers United), Star Sport Academy and African Stars. San-Pédro host Nouadhibou on 17 October at 16:00 GMT.

The round closes on 25 October with ASEC Mimosas v Maghreb Fès and Al Hilal Omdurman v Sidama Bunna, both at 16:00 GMT.

Full schedule, tables and live scores: CAF Champions League fixtures.